Depiction of dihydrofolate reductase (or DHFR), a folate-dependant enzyme required for the biosynthesis of both pyrimidine and purine nucleotides.
Part of a series of illustrations created for the ALIMTA Mechanism of Action, a project we produced (with the direction of GSW) to gain a better understanding of folate metabolism and the process of multitargeted antifolate therapy.
