This animation delves deep into the tumor microenvironment (TME) — a complex cellular domain in which a tumor resides.
Take an immersive, cinematic journey through this thriving tumor microenvironment, showcasing the intricate biological landscape of an extracellular matrix, newly-forming blood vessels, cancer-associated fibroblasts, and various immune cells such as macrophages, T cells, B cells, dendritic cells, neutrophils, NK cells, and more.
Tumors are more than just masses of malignant cells. Although the composition of the TME varies between tumor types, in many cases, the actual tumor cells might comprise less than half of the tumor’s total mass.
In this exploration, we also emphasize cell migration — a critical, multifaceted process shaped by various factors. Cells within the TME communicate with each other through an intricate network of signaling pathways that can influence immune response and surveillance, angiogenesis, tumor growth, metastasis, and resistance to therapies.
