TNF-alpha binding to TNF surface receptors on a synovial fibroblast, leading to stimulation of cell to secrete multiple pro-inflammatory substances that cause synovial inflammation.
Feature hero illustration created for client for use in marketing and collateral materials.
We also produced a 5-minute mechanism of action animation that detailed the client’s innovations involving transgenic technology.
A sequence from this animation appears in the 2010 promotional reel.