Excerpt from a production that discusses T cell inflamed (“hot”) tumors and non T cell inflamed (“cold”) tumors.
Here in this tumor microenvironment landscape, activated immune cells are ready to destroy a tumor — unless the cancer cells manage to fool the T cells into ignoring them when they arrive.
Scientists are looking into the mechanisms that determine the migration of immune cells into the tumor microenvironment and investigating ways to reawaken the ones that have already found their way inside.